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Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge Suberea clavata (Pulitzer-Finali, 1982) ArchiMer
Moriou, Céline; Lacroix, Damien; Petek, Sylvain; El-demerdash, Amr; Trepos, Rozenn; Leu, Tinihauarii Mareva; Florean, Cristina; Diederich, Marc; Hellio, Claire; Debitus, Cecile; Al-mourabit, Ali.
Chemical investigation of the South-Pacific marine sponge Suberea clavata led to the isolation of eight new bromotyrosine metabolites named subereins 1–8 (2–9) along with twelve known co-isolated congeners. The detailed configuration determination of the first representative major compound of this family 11-epi-fistularin-3 (11R,17S) (1) is described. Their chemical characterization was achieved by HRMS and integrated 1D and 2D NMR (nuclear magnetic resonance) spectroscopic studies and extensive comparison with literature data. For the first time, a complete assignment of the absolute configurations for stereogenic centers C-11/17 of the known members (11R,17S) 11-epi-fistularin-3 (1) and 17-deoxyfistularin-3 (10) was determined by a combination of...
Tipo: Text Palavras-chave: Sponge; Verongiida; Suberea clavata; Bromotyrosine; Fistularin-3; Acetylcholinesterase inhibition; Antifouling.
Ano: 2021 URL: https://archimer.ifremer.fr/doc/00684/79581/82258.pdf
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Development of alginate hydrogels active against adhesion of microalgae ArchiMer
Nassif, L. Abi; Rioual, S.; Trepos, Rozenn; Fauchon, M.; Farah, W.; Hellio, C.; Abboud, M.; Lescop, B..
Microorganisms have the ability to settle on nearly all man-made surfaces in contact with seawater and subsequently to form biofilm. Biofilms control and removal is necessary in the sectors of maritime transport, energy... In this work, we present the development of new pure calcium, zinc or copper alginate, but also mixed Ca/Cu and Ca/Zn alginate hydrogels. These materials have been evaluated for their potential inhibition of adhesion of two key biofilm-forming microalgae Halamphora coffeaeformis and Cylindrotheca closterium). All the tested materials have presented high adhesion inhibition about 80%). Copper-base materials present a high toxicity against H. coffeaeformis. Pure zinc alginate is also toxic for this strain. However, the addition of calcium...
Tipo: Text Palavras-chave: Biofilm; Adhesion; Alginate; Zinc; Biomaterials; Microalgae.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00605/71671/70168.pdf
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From Ecology to Biotechnology, Study of the Defense Strategies of Algae and Halophytes (from Trapani Saltworks, NW Sicily) with a Focus on Antioxidants and Antimicrobial Properties ArchiMer
Messina, Concetta Maria; Renda, Giuseppe; Laudicella, Vincenzo Alessandro; Trepos, Rozenn; Fauchon, Marilyne; Hellio, Claire; Santulli, Andrea.
This study aimed at the characterization of the antioxidant power of polyphenol extracts (PE) obtained from the algae Cystoseira foeniculacea (CYS) (Phaeophyta) and from the halophyte Halocnemum strobilaceum (HAL), growing in the solar saltworks of western Sicily (Italy), and at the evaluation of their anti-microfouling properties, in order to correlate these activities to defense strategies in extreme environmental conditions. The antioxidant properties were assessed in the PE based on the total antioxidant activity test and the reducing power test; the anti-microfouling properties of the two PE were evaluated by measuring the growth inhibition of marine fish and shellfish pathogen bacteria as well as marine surface fouling bacteria and microalgae exposed...
Tipo: Text Palavras-chave: Polyphenols; Defenses; Anti-oxidants; Antifouling; Anti-microbial; Cystoseira foeniculacea; Halocnemum strobilaceum.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00605/71675/70090.pdf
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Glycoglycerolipids From Sargassum vulgare as Potential Antifouling Agents ArchiMer
Plouguerné, Erwan; De Souza, Lauro M.; Sassaki, Guilherme L.; Hellio, Claire; Trepos, Rozenn; Da Gama, Bernardo A. P.; Pereira, Renato Crespo; Barreto-bergter, Eliana.
Unraveling new environmentally friendly antifouling (AF) agents is one of the major quests currently facing marine biotechnology. Marine macroalgae represent a rich source of new compounds with promising biological properties, including AF activity, but most of the macroalgal compounds studied to date are terpenoids or polyphenolics. The aim of this work was to investigate the possible AF role played by a usually neglected class of marine natural products: glycolipids (monogalactosyldiacylglycerols – MGDG, digalactosyldiacylglycerols – DGDG and sulfoquinovosyldiacylglycerols – SQDG) isolated from the Phaeophyceae Sargassum vulgare collected along the coast of south-eastern Brazil. Among the 18 extracts, fractions and sub-fractions tested, 3 sub-fractions...
Tipo: Text Palavras-chave: Sargassum vulgare; Glycoglycerolipids; Antifouling; Microfouling; Macroalgae.
Ano: 2020 URL: https://archimer.ifremer.fr/doc/00618/73053/72168.pdf
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